Francis de Sales was born in 1567 into a noble Savoyard family, the eldest son of a father who had mapped out a legal and aristocratic career for him. He pursued that path obediently enough, studying law at Padua, but by the time he returned home he had resolved on the priesthood instead. The resulting conflict with his father was protracted and painful, and it was settled only through patient negotiation rather than dramatic rupture — a pattern that would characterize his entire life.

He was ordained in 1593 and almost immediately sent on a mission to the Chablais, a region of Savoy that had been Protestant for two generations. He worked there for four years largely without visible success, enduring isolation, physical danger, and cold, continuing to write and distribute his arguments even when no one would receive him at a door. He was appointed Bishop of Geneva in 1602, a diocese whose cathedral city was Calvin's stronghold and therefore wholly inaccessible to him; he governed it from Annecy for the rest of his life. There he met Jeanne de Chantal, with whom he founded the Visitation of Holy Mary, a congregation designed for women whose health or family obligations barred them from the austerities of existing orders.

His lasting influence rests chiefly on two works. The Introduction to the Devout Life, assembled from letters of spiritual direction and published in 1609, argued with quiet persistence that the pursuit of holiness was not confined to monasteries but was available to merchants, soldiers, married people, and courtiers — anyone willing to attend to the ordinary moments of a day. The Treatise on the Love of God followed in 1616, a longer and more systematic exploration of the will's movement toward God. His prose is gentle without being soft, and his counsel consistently practical.

He was canonized in 1665 and named a Doctor of the Church in 1877; in 1923 Pius XI declared him patron of writers and journalists, a recognition of what patient, ordinary language in the service of faith can accomplish.